It's official: America likes talking stuffed animals more than naked men.
Despite strong competition from Channing Tatum and the shirtless strippers of Magic Mike, Ted smoked and cursed his way to the top of the box office this weekend, earning $54.1 million on Friday and Saturday.
It was the third-highest debut of all-time for an R-rated comedy, trailing only The Hangover II and Sex and the City.
Magic Men didn't fare too poorly itself, though, pulling in a 73 percent female audience and garnering $39.2 million in two days.
“This is what the business is about,” says Warner Brothers’ President of Domestic Distribution, Dan Fellman. “There are surprises sometimes, and when you get a sleeper, it’s great.”
Addiction-related process may keep people hurting long after an injury heals
Web edition : 8:52 pm
A signal in the brain can predict who will continue to suffer back pain more than a year after an initial injury. This early warning sign could reveal new ways to reverse or prevent pain that lingers long after an injury heals, scientists report online July 1 in Nature Neuroscience.
?We?re very excited about these results,? says study coauthor A. Vania Apkarian of Northwestern University in Evanston, Ill. ?We think they open up a whole new way of looking at chronic pain.?
The study included 39 people with newish back pain, about half of whom still suffered a full year later. These people?s pain had turned chronic, morphing from the pain associated with the original problem to something more devastating. At the start, pain intensity was similar in people with chronic pain and in those who recovered.
But people whose pain turned chronic had an unusually strong connection between two parts of their brains: the nucleus accumbens and the prefrontal cortex. These two regions behaved in tandem, brain scans revealed, so that when one was busy the other was too. The strength of this connection predicted which participants would have lingering pain a full year later: The stronger the connection, the more susceptible a person was to chronic pain.
?This is something we can study,? says neuroscientist Laura Stone of McGill University in Montreal. ?We can figure out how to target this to prevent that transition.?
Earlier studies have catalogued brain differences in people with chronic pain and healthy controls, but researchers never knew whether such differences were the cause of chronic pain or an effect of living with it. This study is the first to uncover a signal that?s present before pain becomes chronic, Stone says.
The study may also link chronic pain development to the brain?s addiction machinery, which includes the nucleus accumbens. ?This is certainly part of the addiction pathway,? Apkarian says. Though the idea hasn?t been tested, he says, chronic pain may stem from the brain essentially becoming addicted to pain.
Stone says the concept of pain co-opting the addiction circuitry in the brain makes a lot of sense, but it?s too early to say whether that idea is right.
Frances Lukens looks at the tangle of boards and tree limbs piercing her living room ceiling in Lynchburg, Va. on Saturday, June 30, 2012 after a huge oak tree fell directly on the house during a storm the previous night. (AP Photo/The News & Advance, Parker Michels-Boyce)
Frances Lukens looks at the tangle of boards and tree limbs piercing her living room ceiling in Lynchburg, Va. on Saturday, June 30, 2012 after a huge oak tree fell directly on the house during a storm the previous night. (AP Photo/The News & Advance, Parker Michels-Boyce)
Lighting flashes Saturday morning, June, 30, 2012 in Hebron Md.. Violent storms swept across the eastern U.S., killing at least nine people and knocking out power to hundreds of thousands on a day that temperatures across the region are expected to reach triple-digits. (AP photo by Salisbury Daily Times, Kristin Roberts)
A Lynchburg City worker ties power lines above a traffic signal at Oakley and Memorial Avenues, July 1, 2012. Two days after storms tore across the eastern U.S., power outages were forcing people to get creative to stay cool in dangerously hot weather. Temperatures approached 100 degrees in many storm-stricken areas, and utility officials said the power will likely be out for several more days. (AP Photo/The News & Advance, Parker Michels-Boyce)
Gary Davis tosses aside a section of a Tulip Poplar tree the fell behind a friend's house on Greenwood Drive in Lynchburg, Va., July 1, 2012. The tree fell between two houses, narrowly sparing both. (AP Photo/The News & Advance, Parker Michels-Boyce)
A car sits, crushed by a fallen tree, on Carrington Road in Lynchburg, Va., July 1, 2012. Two days after storms tore across the eastern U.S., power outages were forcing people to get creative to stay cool in dangerously hot weather. Temperatures approached 100 degrees in many storm-stricken areas, and utility officials said the power will likely be out for several more days. (AP Photo/The News & Advance, Parker Michels-Boyce)
WASHINGTON (AP) ? A weekend without electricity was already trying for millions in the sweltering, storm-swept mid-Atlantic region. But Monday morning brings another grim challenge when many embark on a difficult commute over roads with darkened stoplights and likely mass-transit delays.
To alleviate congestion around Baltimore and Washington, federal and state officials gave many workers the option of staying home Monday. Federal agencies will be open in Washington, but non-emergency employees have the option of taking leave or working from home. Maryland's governor also gave state workers wide leeway for staying out of the office.
There were more than 500 signal outages in Maryland on Sunday afternoon, including more than 400 in hard-hit Montgomery County outside the nation's capital, according to the State Highway Administration. There were 100 signal outages in northern Virginia late Sunday afternoon, and 65 roads were closed, although most were secondary roads.
"If you have to drive or need to drive, leave yourself a lot of extra time," Maryland State Highway Administration spokesman Charlie Gischlar said. "There's going to be delays."
All 86 Metro subway stations in the Washington area were open, but delays were possible Monday because power was being routed through the system to serve some areas where power was not being supplied by commercial utilities, spokesman Dan Stessel said. Some stations in Montgomery County were running on backup power, he said, meaning escalators may not work ? bad news for commuters braving the stifling heat. Metro bus riders were expected to experience significant delays.
As of late Sunday, nearly 2.7 million people remained without power in several states from Virginia to New Jersey and as far west as Ohio. That left many to contend with stifling homes and spoiled food as temperatures approached or exceeded 100 degrees, and utility officials said the power will likely be out for several more days. Since Friday, severe weather has been blamed for at least 17 deaths, most from trees falling on homes and cars.
Meanwhile, Coast Guard officials say they have suspended the search for a man who disappeared early Saturday while boating during the storm off Maryland.
On Sunday night in North Carolina, a 77-year-old man was killed when strong winds collapsed a Pitt County barn where he was parking an all-terrain vehicle, authorities said. In neighboring Beaufort County, a couple was killed when a tree fell on the golf cart they were driving. Officials said trees fell onto dozens of houses, and two hangars were destroyed at an airport in Beaufort County.
The damage was mostly blamed on straight-line winds, which are strong gusts pushed ahead of fast-moving thunderstorms like a wall of wind.
Elsewhere, at least six of the dead were killed in Virginia, including a 90-year-old woman asleep in her bed when a tree slammed into her home. Two young cousins in New Jersey were killed when a tree fell on their tent while camping. Two were killed in Maryland, one in Ohio, one in Kentucky and one in Washington.
For survivors, it was a challenge to stay cool over the weekend.
From Atlanta to Baltimore, temperatures approached or exceeded triple digits. Atlanta set a record with a high of 105 degrees, while the temperature hit 99 at Ronald Reagan Washington National Airport just outside the nation's capital. With no air conditioning, officials urged residents to check on their elderly relatives and neighbors. It was tough to find a free pump at gas stations that did have power, and lines of cars snaked around fast-food drive-thrus.
"If we don't get power tonight, we'll have to throw everything away," Susan Fritz, a mother of three, said grimly of her refrigerator and freezer. Fritz came to a library in Bethesda, Md., so her son could do school work. She charged her phone and iPad at her local gym.
Power crews from as far away as Florida and Oklahoma were on their way to the mid-Atlantic region to help get the power back on and the air conditioners running again. Even if people have generators, the gas-run devices often don't have enough power to operate an air conditioner.
And power restoration was spotty: Several people interviewed by The Associated Press said they remained without power even though the lights were on at neighbors' homes across the street. In Maryland, Gov. O'Malley promised he would push utility companies to get electricity restored as quickly as possible.
"No one will have his boot further up Pepco's and BGE's backsides than I will," O'Malley said Sunday afternoon, referring to the two main utilities serving Maryland.
In Waldorf, Md., Charles County emergency officials handed out free 40-pound bags of ice to anyone who needed them. Among the takers was Ann Brown, 47, of Accokeek, Md., who had stayed in a hotel Saturday night because her house was without power.
She went to a cookout in Upper Marlboro, Md., on Saturday after family members decided to cook all the food in the freezer rather than let it go bad.
"Whatever they had, that's what we ate, and it was great," Brown said.
Whether she makes the commute to work Monday will depend entirely on how comfortable the office is.
"If they don't have power, I'm not going. But if they have power, yeah, I'm going in, to be in the air conditioning all day," she said.
In suburban Fairfax County, Va., residents cooled off at pools, recreation centers, libraries, restaurants and shopping malls. Many residents said they weren't especially prepared for an extended outage.
Tracy Standish, who lives on Fort Belvoir with her husband who's in the military, brought her two teenage sons to an air-conditioned recreation center Sunday morning that had been designated as a cooling center by the county.
"Pick a table and make yourselves at home for the next 2-3 hours," she told her sons.
Janice Tuten and her husband brought coffee, backpacks, laptops, cell phones ? and chargers for everything ? to the Arlington library, where they hoped to settle in for the long haul. They spent about six hours at the library Saturday. Asked how long they planned to stay Sunday, Tuten asked, "What time does it close?"
___
Associated Press writers Jessica Gresko in Waldorf, Md.; Stacy A. Anderson in Bethesda, Md.; Steve Szkotak in Lakeside, Va.; Jonathan Drew in Atlanta; and Dan Sewell in Cincinnati contributed to this report.
Secrets of lung cancer drug resistance revealed at UCSFPublic release date: 1-Jul-2012 [ | E-mail | Share ]
Contact: Jason Socrates Bardi jason.bardi@ucsf.edu 415-502-6397 University of California - San Francisco
Discovery may lead to new, more powerful precision medicines that thwart resistance to the common lung cancer drug Tarceva
People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will returnit's a question of when. And for far too many, it happens far too soon.
Now, a team of researchers at the University of California, San Francisco's Helen Diller Family Comprehensive Cancer Center has discovered that a human protein called AXL drives resistance to Tarceva, which suggests that blocking the protein may prevent resistance to the cancer drug.
The discovery, described this week in Nature Genetics, may lead to better treatments involving precision medicines that would combine Tarceva with new drugs designed to block AXL.
"If we block AXL activation in the laboratory, we can overcome resistance to Tarceva," said Trever Bivona, MD, PhD, an assistant professor of hematology and oncology. "This paves the way for novel and more effective therapies."
In the experiments, Bivona and his colleagues used an inhibitor of AXL that is not an ideal clinical drug. But now Bivona and his team are working together with Kevan Shokat, PhD, a Howard Hughes Medical Institute Investigator and chair of the UCSF Department of Cellular and Molecular Pharmacology, to develop more potent AXL inhibitors for clinical testing.
Lung Cancer is Number One Cancer Killer
Lung cancer is the most common cause of cancer death worldwide. More people die from the disease each year than from breast, colon and prostate cancers combined. It claims more than 150,000 American lives annually and accounts for some 1.4 million deaths around the world. About 85 percent of Americans with all types of lung cancer die within five years of diagnosis.
Most cases result from exposure to cigarette smoke, but other causes include exposure to asbestos, chemicals, environmental factors and genetic susceptibility.
One thing that makes lung cancer so difficult is that it often goes undetected in its early stages because it usually does not cause symptoms. Only about 30 percent of patients in the United States are detected in the earliest stage of the disease, contributing to its low overall survival rate.
Even people who have their cancer detected at the earliest stages, however, face serious odds. Unlike other types of cancer, where early diagnosis has significant survival advantages, some 35 to 45 percent of people with stage I lung cancer die within five years of recurrent disease.
Though treatment varies depending on the type of lung cancer, its stage, and whether it not it has metastasized to regional lymph nodes, standard treatments usually involve surgery or some combination of surgery, radiation therapy and chemotherapy.
Tarceva is one such chemotherapy drug. Also known as erlotinib, the drug is a targeted therapy that works by blocking an enzyme known as epidermal growth factor receptor (EGFR). Bivona and his colleagues discovered that AXL drives resistance to Tarceva by "rescuing" lung cancers from EGFR inhibitor treatment.
AXL, said Bivona, is the sort of molecule known as a kinase, which makes it a valuable target for drug design. Many of the existing targeted cancer drugs on the market, including Tarceva, work by blocking kinases in one form or another.
###
The article, "Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer," by Zhenfeng Zhang, Jae Cheol Lee, Luping Lin, Victor Olivas, Valerie Au, Thomas LaFramboise, Mohamed Abdel-Rahman, Xiaoqi Wang, Alan D Levine, Jin Kyung Rho, Yun Jung Choi, Chang-Min Choi, Sang-We Kim, Se Jin Jang, Young Soo Park, Woo Sung Kim, Dae Ho Lee, Jung-Shin Lee, Vincent A Miller, Maria Arcila, Marc Ladanyi, Philicia Moonsamy, Charles Sawyers, Titus J Boggon, Patrick C Ma, Carlota Costa, Miquel Taron, Rafael Rosell, Balazs Halmos and Trever G Bivona, will be published on the Nature Genetics website on July 1, 2012. After that time the paper can be accessed at: http://dx.doi.org/0.1038/ng.2330.
In addition to UCSF, authors on this study are affiliated with Case Western Reserve University in Cleveland, Columbia University in New York, the University of Alsan in Seoul, Korea, Memorial Sloan-Kettering Cancer Center in New York, Yale University, Hospital Germans Trias i Pujol in Barcelona, Spain, and USP Dexeus University Institute in Barcelona, Spain.
This work was supported by the National Institutes of Health through grants K08 1K08CA154787 and P01 CA129243. Additional support was provided through a Uniting Against Lung Cancer Research Award, a National Lung Cancer Partnership Young Investigator Award, a grant from the La Caixa Foundation, an American Cancer Society Research Scholar Grant, and a Korean Health Technology R&D Project.
UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Secrets of lung cancer drug resistance revealed at UCSFPublic release date: 1-Jul-2012 [ | E-mail | Share ]
Contact: Jason Socrates Bardi jason.bardi@ucsf.edu 415-502-6397 University of California - San Francisco
Discovery may lead to new, more powerful precision medicines that thwart resistance to the common lung cancer drug Tarceva
People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will returnit's a question of when. And for far too many, it happens far too soon.
Now, a team of researchers at the University of California, San Francisco's Helen Diller Family Comprehensive Cancer Center has discovered that a human protein called AXL drives resistance to Tarceva, which suggests that blocking the protein may prevent resistance to the cancer drug.
The discovery, described this week in Nature Genetics, may lead to better treatments involving precision medicines that would combine Tarceva with new drugs designed to block AXL.
"If we block AXL activation in the laboratory, we can overcome resistance to Tarceva," said Trever Bivona, MD, PhD, an assistant professor of hematology and oncology. "This paves the way for novel and more effective therapies."
In the experiments, Bivona and his colleagues used an inhibitor of AXL that is not an ideal clinical drug. But now Bivona and his team are working together with Kevan Shokat, PhD, a Howard Hughes Medical Institute Investigator and chair of the UCSF Department of Cellular and Molecular Pharmacology, to develop more potent AXL inhibitors for clinical testing.
Lung Cancer is Number One Cancer Killer
Lung cancer is the most common cause of cancer death worldwide. More people die from the disease each year than from breast, colon and prostate cancers combined. It claims more than 150,000 American lives annually and accounts for some 1.4 million deaths around the world. About 85 percent of Americans with all types of lung cancer die within five years of diagnosis.
Most cases result from exposure to cigarette smoke, but other causes include exposure to asbestos, chemicals, environmental factors and genetic susceptibility.
One thing that makes lung cancer so difficult is that it often goes undetected in its early stages because it usually does not cause symptoms. Only about 30 percent of patients in the United States are detected in the earliest stage of the disease, contributing to its low overall survival rate.
Even people who have their cancer detected at the earliest stages, however, face serious odds. Unlike other types of cancer, where early diagnosis has significant survival advantages, some 35 to 45 percent of people with stage I lung cancer die within five years of recurrent disease.
Though treatment varies depending on the type of lung cancer, its stage, and whether it not it has metastasized to regional lymph nodes, standard treatments usually involve surgery or some combination of surgery, radiation therapy and chemotherapy.
Tarceva is one such chemotherapy drug. Also known as erlotinib, the drug is a targeted therapy that works by blocking an enzyme known as epidermal growth factor receptor (EGFR). Bivona and his colleagues discovered that AXL drives resistance to Tarceva by "rescuing" lung cancers from EGFR inhibitor treatment.
AXL, said Bivona, is the sort of molecule known as a kinase, which makes it a valuable target for drug design. Many of the existing targeted cancer drugs on the market, including Tarceva, work by blocking kinases in one form or another.
###
The article, "Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer," by Zhenfeng Zhang, Jae Cheol Lee, Luping Lin, Victor Olivas, Valerie Au, Thomas LaFramboise, Mohamed Abdel-Rahman, Xiaoqi Wang, Alan D Levine, Jin Kyung Rho, Yun Jung Choi, Chang-Min Choi, Sang-We Kim, Se Jin Jang, Young Soo Park, Woo Sung Kim, Dae Ho Lee, Jung-Shin Lee, Vincent A Miller, Maria Arcila, Marc Ladanyi, Philicia Moonsamy, Charles Sawyers, Titus J Boggon, Patrick C Ma, Carlota Costa, Miquel Taron, Rafael Rosell, Balazs Halmos and Trever G Bivona, will be published on the Nature Genetics website on July 1, 2012. After that time the paper can be accessed at: http://dx.doi.org/0.1038/ng.2330.
In addition to UCSF, authors on this study are affiliated with Case Western Reserve University in Cleveland, Columbia University in New York, the University of Alsan in Seoul, Korea, Memorial Sloan-Kettering Cancer Center in New York, Yale University, Hospital Germans Trias i Pujol in Barcelona, Spain, and USP Dexeus University Institute in Barcelona, Spain.
This work was supported by the National Institutes of Health through grants K08 1K08CA154787 and P01 CA129243. Additional support was provided through a Uniting Against Lung Cancer Research Award, a National Lung Cancer Partnership Young Investigator Award, a grant from the La Caixa Foundation, an American Cancer Society Research Scholar Grant, and a Korean Health Technology R&D Project.
UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Chicago?s firearm buyback program, titled ?Don?t kill a dream, save a life,? aims to get dangerous weapons off the street. But a pro-gun rights group gleefully says it used the program to turn in ?non-firing junk? to raise money for a National Rifle Association youth shooting camp.
Guns Save Life, based in Champaign, Ill., three hours south of Chicago, turned in?dozens of?guns and BB guns it had collected ? ?rusty scrap metal,? the group called the load ? taking home $6,240.
Of the 5,500 guns turned in on June 23, 60 came from Guns Save Life.
The Chicago Police Department program pays $100 for every gun and $10 every BB gun, air gun or replica, no questions asked. The money is given in the form of a Visa debit card.
?We are redirecting funds from people who would work against the private ownership of firearms to help introduce the next generation to shooting safely and responsibly,? John Boch, head of Guns Save Life, told the Chicago Sun-Times.
Boch said the money will go toward paying for ammunition for the youth camp.
Police spokeswoman Melissa Stratton was not amused, according to the Sun-Times.
?It?s unfortunate that this group is abusing a program intended to increase the safety of our communities,? Stratton said.
More content from msnbc.com and NBC News:
Follow US News on msnbc.com on Twitter and Facebook
JERUSALEM?? Yitzhak Shamir, the hawkish Israeli leader who balked at the idea of trading occupied land for peace with the Palestinians, died on Saturday after a long illness. He was 96.
Only on msnbc.com
American mauled by chimps has 6-hours surgery
Chicago gun buyback raises money for NRA kids' camp
Families brace for mental health cuts
Pelosi: GOP mouthpiece for health insurers
Caught on tape: Adults behaving badly
Egypt turns new page; citizens await results
He was twice prime minister in the 1980s and early 1990s. Rather than seek accommodation with the Palestinians, Shamir championed new Jewish settlements.
Israeli media said Shamir, who had Alzheimer's disease, died at a nursing home in Herzliya Saturday.
Shamir served as prime minister for seven years, from 1983-84 and 1986-92, leading his party to election victories twice, despite lacking much of the outward charm and charisma that characterizes many modern politicians.
"Yitzhak Shamir was a brave warrior for Israel, before and after its inception. He was a great patriot and his enormous contribution will be forever etched in our chronicles," President Shimon Peres said in a statement obtained by YNet news of Israel.
"Yitzhak Shamir belongs to a generation of giants, who founded the State of Israel and fought for the freedom of the Jewish people in its land," Prime Minister Benjamin Netanyahu said. "He led Israel with deep loyalty to both the people and the land."
Gilada Diamant, Shamir's daughter, said that her father "belonged to a different generation of leaders, people with values and beliefs. I hope that we have more people like him in the future. His political doing has undoubtedly left its mark on the State of Israel.
"Dad was an amazing man, a family man in the fullest sense of the word, a man who dedicated himself to the State of Israel but never forgot his family, not even for a moment. He was a special man," she added.
Barely over 5 feet tall and built like a block of granite, Shamir projected an image of uncompromising solidity at a time when Palestinians rose up in the West Bank and Gaza, demanding an end to Israeli occupation.
Defeated in the 1992 election, he stepped down as head of the Likud party and watched from the sidelines as his successor, Yitzhak Rabin, negotiated interim land-for-peace agreements with the Palestinians.
The agreements, including Palestinian leader Yasser Arafat's recognition of Israel, did nothing to ease his suspicion. In a 1997 interview with the New York-based Jewish Post, he declared: "The Arabs will always dream to destroy us. I do not believe that they will recognize us as part of this region."
He embraced the ideology of the Revisionists -- that Israel is the sole owner of all of the biblical Holy Land, made up of Israel, the West Bank and Jordan.
The Labor movement, in power for Israel's first three decades, agreed to a 1947 U.N.-proposed partition plan to allow the creation of the Jewish state alongside a Palestinian entity. To Shamir and other Revisionists, that was tantamount to treason.
In later years, asked his view of territorial compromise for peace, Shamir said often that Israel had already given up 80 percent of the Land of Israel ? a reference to Jordan.
Polish born
Born Yitzhak Jazernicki in Poland in 1915, he moved to pre-state Palestine in 1935. He joined Lehi, the most hardline of three Jewish movements resisting British mandatory authorities, taking over the Lehi leadership after the British killed its founder.
Captured twice, he escaped from two British detention camps and returned to resistance action. The second camp was in Djibouti, in Africa.
After Israel was founded in 1948, Shamir was in business for a few years before entering a career in Israel's Mossad spy agency.
In the mid-1960s he emerged to join the right-wing Herut party, which evolved into the present-day Likud.
Shamir succeeded Menahem Begin as prime minister in 1983 in the aftermath of Israel's disastrous 1982 invasion of Lebanon.
His term was marked by the Palestinian uprising against Israeli occupation, and the 1991 Gulf war, when Iraq fired 39 Scud missiles at Israel.
Arguing with the US
During the Gulf war, Shamir went along with American demands not to retaliate for the Iraqi missile strikes. After the war, the United States stepped up pressure to start a Middle East process that could lead in only one direction ? compromise with the Arabs.
Exasperated by Shamir's stubborn refusal to go along with their plans for a regional settlement, then-U.S. Secretary of State James Baker once went on television, recited the switchboard number of the White House and told Shamir to call when he got serious about peace.
In the end, American pressure bent even Shamir. Despite his deep mistrust of Arab intentions, he agreed to attend the 1991 Middle East peace conference in Madrid, sponsored by the United States and Russia.
Shamir hotly rejected the deals his successors made with the Palestinians, in which Israel turned over control of some West Bank land to the Palestinians.
His pleasure at the 1996 election victory of Likud leader Benjamin Netanyahu soured when Netanyahu continued to negotiate with the Palestinians and carry out land-for-security deals.
Before the 1999 election, Shamir resigned from the Likud and joined a new right-wing block called National Union, headed by Begin's son, Ze'ev Binyamin.
The party, which rejected any turnover of land to the Palestinians, won only four seats in parliament, though it had seven members of the outgoing legislature on its list.
In 2001, Shamir was given his nation's highest civilian honor, the Israel Prize awarded annually to outstanding citizens in several fields.
Shamir will receive a state funeral, which has been set for Monday, YNet reported. He will be laid to rest in the Nation's Great cemetery on Mount Hertz.
Reuters and The Associated Press contributed to this report.
[ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]
[ [ [['did not go as far his colleague', 8]], '29438204', '0' ], [ [[' the 28-year-old neighborhood watchman who shot and killed', 4]], '28924649', '0' ], [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 1-Jul-2012
Share ]